CHEMICAL_NAME	STUDY_TITLE	ACCESSION_NUMBER	ORGANIZATION_NAME	START_DATE	STUDY_DURATION	STUDY_DURATION_UNIT	ACTIVE_CONCENTRATION	ACTIVE_CONCENTRATION_UNIT	BIOLOGICAL_CLASS_AGENT	DOSE_FREQUENCY	DOSE_FREQUENCY_UNIT	DOSE_FREQUENCY_DESC	PROTOCOL_DETAILS	VEHICLE_NAME	VEHICLE_COMMENT	TIME_IN_STUDY	TIME_IN_STUDY_UNIT	GROUP_NAME	COMPARATOR_NAME	CELL_LINE	DOSE	DOSE_UNIT	DOSE_DURATION	DOSE_DURATION_UNIT	CHEM_STRESSOR_CLASS	DOUBLING_TIME	DOUBLING_TIME_UNIT	GENUS	IS_ADHERENT	IS_CELLLINE_TRANSFORMED	ORIGINAL_CELL_TYPE	SUBJECT_NAME	SPECIES_COMMON_NAME	ONE8S_MEAN	ONE8S_STDEV	ACTB_MEAN	ACTB_STDEV	APEX1_MEAN	APEX1_STDEV	ATF3_MEAN	ATF3_STDEV	AURKA_MEAN	AURKA_STDEV	B2M_MEAN	B2M_STDEV	BAX_MEAN	BAX_STDEV	BCL2_MEAN	BCL2_STDEV	CASP1_MEAN	CASP1_STDEV	CCNG1_MEAN	CCNG1_STDEV	CDKN1A_MEAN	CDKN1A_STDEV	CDKN1C_MEAN	CDKN1C_STDEV	DDB2_MEAN	DDB2_STDEV	DDIT3_MEAN	DDIT3_STDEV	DNAJB1_MEAN	DNAJB1_STDEV	EIF1_MEAN	EIF1_STDEV	FOS_MEAN	FOS_STDEV	G3BP2_MEAN	G3BP2_STDEV	GADD45A_MEAN	GADD45A_STDEV	GADD45B_MEAN	GADD45B_STDEV	GADD45G_MEAN	GADD45G_STDEV	GAPDH_MEAN	GAPDH_STDEV	GDF15_MEAN	GDF15_STDEV	GSTA2_MEAN	GSTA2_STDEV	GZMA_MEAN	GZMA_STDEV	GZMB_MEAN	GZMB_STDEV	H2AFX_MEAN	H2AFX_STDEV	HERPUD1_MEAN	HERPUD1_STDEV	HIST1H1C_MEAN	HIST1H1C_STDEV	HIST1H2AC_MEAN	HIST1H2AC_STDEV	HSPA14_MEAN	HSPA14_STDEV	HSPA5_MEAN	HSPA5_STDEV	IL1B_MEAN	IL1B_STDEV	INCENP_MEAN	INCENP_STDEV	JUNB_MEAN	JUNB_STDEV	LEF1_MEAN	LEF1_STDEV	MAK_MEAN	MAK_STDEV	MATR3_MEAN	MATR3_STDEV	MCL1_MEAN	MCL1_STDEV	MDM2_MEAN	MDM2_STDEV	NDUFA1_MEAN	NDUFA1_STDEV	PCNA_MEAN	PCNA_STDEV	PHLDA3_MEAN	PHLDA3_STDEV	PLK1_MEAN	PLK1_STDEV	PPM1D_MEAN	PPM1D_STDEV	SAC3D1_MEAN	SAC3D1_STDEV	SHD1_MEAN	SHD1_STDEV	SP3_MEAN	SP3_STDEV	TOB1_MEAN	TOB1_STDEV	TOP1_MEAN	TOP1_STDEV	TOP2A_MEAN	TOP2A_STDEV	TP53I3_MEAN	TP53I3_STDEV	VAMP3_MEAN	VAMP3_STDEV	XPC_MEAN	XPC_STDEV
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	0.1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	26	hour	2_TK6_Tax_M1_2_hr	2_TK6_Tax_0_2_hr	TK6	M1	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	0.1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	2_TK6_Tax_M1_4_hr	2_TK6_Tax_0_4_hr	TK6	M1	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	0.1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	31	hour	2_TK6_Tax_M1_7_hr	2_TK6_Tax_0_7_hr	TK6	M1	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	2_TK6_Tax_M2_24_hr	2_TK6_Tax_0_24_hr	TK6	M2	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	26	hour	2_TK6_Tax_M2_2_hr	2_TK6_Tax_0_2_hr	TK6	M2	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	2_TK6_Tax_M2_4_hr	2_TK6_Tax_0_4_hr	TK6	M2	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	1	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	31	hour	2_TK6_Tax_M2_7_hr	2_TK6_Tax_0_7_hr	TK6	M2	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	10	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	2_TK6_Tax_H_24_hr	2_TK6_Tax_0_24_hr	TK6	H	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	10	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	26	hour	2_TK6_Tax_H_2_hr	2_TK6_Tax_0_2_hr	TK6	H	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	10	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	2_TK6_Tax_H_4_hr	2_TK6_Tax_0_4_hr	TK6	H	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Taxol	2_TK6_Cisplatin-Taxol	008-00004-0005-000-7	HESI	2004	48	hour	10	ug/ml	Mitotic spindle poison	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	31	hour	2_TK6_Tax_H_7_hr	2_TK6_Tax_0_7_hr	TK6	H	ug/ml	4	hour	mitotic spindle poison	24	hour	Homo	F	T	Lymphoid		Human																																																																																																												
Cisplatin	3_TK6_Cisplatin-NaCl-Taxol	008-00004-0006-000-8	HESI	2004	48	hour	1	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	3_TK6_Cis_L_24_hr	3_TK6_DMSO_0_24_hr	TK6	L	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			-0.152003093	0.055677644	-0.234465254	0.086216781	1.929790998	0.162583312	-0.535331733	0.147422296			0.815575429	0.155026879	-0.104697379	0.085440037	1.263034406	0.269629375	0.687060688	0.172143351	2.100977648	0.39715656					1.550900665	0.678011799	-0.76121314	0.043588989	-0.304006187	0.032145503	8.767787198	66.24983245			1.555816155	0.076376262	-0.340075442	0.017320508					3.684818738	0.978587417							0.097610797	0.155349069	-0.217591435	0.065064071	-1.286304185	0.02081666	-1	0.375011111	-0.49410907	0.055075705	-0.577766999	0.036055513	-4.321928095	0.005773503	-0.304006187	0.14571662	0	0.047258156			1.056583528	0.63089883	-0.200912694	0.061101009	-0.200912694	0.058594653	2.220329955	0.319530906	-0.268816758	0.060277138	0.201633861	0.02081666	1.292781749	0.237557011	-0.234465254	0.065574385	0.659924558	0.205182845			-0.76121314	0.132035349			0.263034406	0.055075705	-0.01449957	0.068068593	0.250961574	0.122202019	3.468583317	2.185001907	-0.152003093	0.075718778	0.970853654	1.965
Cisplatin	3_TK6_Cisplatin-NaCl-Taxol	008-00004-0006-000-8	HESI	2004	48	hour	1	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	3_TK6_Cis_L_4_hr	3_TK6_DMSO_0_4_hr	TK6	L	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			0	0.202072594	-0.358453971	0.051800976	1.367371066	0.819768557	-0.321928095	0.204478171			0.056583528	0.105039675	-0.304006187	0.052519799	-0.234465254	0.177684587	0.111031312	0.108544549	1.220329955	0.30219418					-0.184424571	0.201102232	0.344828497	0.068280037	0.111031312	0.085845839	5.29351763	18.71152914			0.650764559	0.171777373	0.454175893	0.151331151					1.713695815	0.525167276							-0.152003093	0.098311063	0.150559677	0.181722362	-0.251538767	0.079066015	-0.286304185	0.16587762	0.014355293	0.094417864	-0.13606155	0.074958354	-1.514573173	0.044837793	-0.104697379	0.149577031	0.263034406	0.191190544			1.516015147	1.447114499	-0.358453971	0.086373286	0.137503524	0.181869723	1.03562391	0.144265126	-0.029146346	0.146855983	0.321928095	0.241934191	0.807354922	0.070187165	-0.689659879	0.105352316	0.367371066	0.218649785			0.454175893	0.656516153			0.042644337	0.148847655	-0.058893689	0.109904274	-0.514573173	0.072841539	0.50589093	0.3053218	-0.074000581	0.077653624	0.411426246	0.093224477
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	1	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	1_TK6_Cis_L_24_hr	1_TK6_Cis_0_24_hr	TK6	L	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			-0.286304185	0.04	-0.200912694	0.02	-0.043943348	0.03	-0.152003093	0.01			-0.13606155	0.00875	-0.01449957	0.04	0	0	-0.251538767	0.01	-0.286304185	0.03	0	0			0.176322773	0.06	0.014355293	0.00545	-0.184424571	0.07	-1.514573173	0.45			-0.168122759	0.02	0	0.03	-0.104697379	1.3			0	0.05	0	0	0	0	0	0	-0.152003093	0.0048	0	0.07	-0.13606155	0.00252	-0.234465254	0.09	-0.184424571	0.00575	0.097610797	0.11	0.124328135	1.18	-0.234465254	0.00436	-0.251538767	0.00947	0	0	-0.358453971	0.01	-0.120294234	0.06	0.014355293	0.11	-0.104697379	0.00662			-0.286304185	0.1	0.042644337	0.02	-0.058893689	0.01	-0.13606155	0.01			-0.01449957	0.27			-0.13606155	0.03	-0.76121314	0.22	-0.184424571	0.06	-0.152003093	0.03	-0.184424571	0.00801	-0.120294234	0.01
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	1	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	1_TK6_Cis_L_4_hr	1_TK6_Cis_0_4_hr	TK6	L	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			-0.089267338	0.09	-0.168122759	0.02	-0.043943348	0.08	-0.49410907	0.09			-0.120294234	0.01	-0.01449957	0.01	0.014355293	0.02	0.014355293	0.02	-0.029146346	0.08	0	0			-0.01449957	0.05	0.097610797	0.08	-0.120294234	0.12	0	0			-0.043943348	0.06	0.014355293	0.06	0.286881148	0.06			-0.029146346	0.00341	0.00339	0.00219	0	0	6.908812908	92.12	-0.058893689	0.05	-0.089267338	0.04	-0.074000581	0.01	0.111031312	0.04	0	0.03	0.014355293	0.06	0.831877241	0.55	-0.200912694	0.02	-0.13606155	0.06	0	0	0.201633861	0.01	0.028569152	0.05	-0.089267338	0.06	0.028569152	0.03			-0.029146346	0.03	0.042644337	0.08	-0.058893689	0.14	-0.120294234	0.08			-0.074000581	0.02			-0.01449957	0.01	-0.074000581	0.08	-0.029146346	0.00816	-0.029146346	0.13	-0.029146346	0.05	0	0.07
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	1	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	31	hour	1_TK6_Cis_L_7_hr	1_TK6_Cis_0_7_hr	TK6	L	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			10	3230216.14	0.014355293	0.06	0.650764559	0.65	-0.321928095	0.25			-0.104697379	0.11	10	3498.97	-0.152003093	0.14	0.014355293	0.08	-0.043943348	0.18	0.084064265	0.09			10	2638.44	0.163498732	0.13	-0.01449957	0.15	-0.058893689	0.68			10	24101.69	0.070389328	0.1	0.214124805	0.23			0.35614381	0.25	-0.59946207	0.47	0	0	8.392317423	451.4	-0.029146346	0.16	0.757023247	0.75	0.014355293	0.05	6.834407842	159.43	0.070389328	0.06	0.613531653	0.67	-0.217591435	0.27	3.436961338	14.05	-0.074000581	0.1	0	0	9.689491367	1162.18	0.028569152	0.13	0.310340121	0.2	0.042644337	0.08			-0.76121314	0.46	0.014355293	0.09	-0.13606155	0.03	-0.168122759	0.14			-0.104697379	0.15			0.056583528	0.19	-0.200912694	0.18	-0.01449957	0.02	-0.01449957	0.09	0.097610797	0.16	0.056583528	0.1
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	10	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	1_TK6_Cis_M_24_hr	1_TK6_Cis_0_24_hr	TK6	M	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			0.422233001	0.29	0.124328135	0.3	0.443606651	0.24	0.40053793	0.25			0.526068812	0.17	0.298658316	0.21	0	0	0.23878686	0.33	0.516015147	0.27	4.535430915	31.38			0.464668267	0.23	0.250961574	0.31	0.137503524	0.2	5.700439718	72.79			0.485426827	0.23	0.176322773	0.17	1.35614381	0.88			0.748461233	0.23	0	0	0	0	7.428108883	183.11	0.35614381	0.2	0.263034406	0.25	-0.152003093	0.4	-0.217591435	0.39	0.056583528	0.35	0.163498732	0.21	1.10433666	1.69	0.475084883	0.26	0.124328135	0.16	0	0	0.056583528	0.07	0.097610797	0.19	0.286881148	0.21	0.454175893	0.21			0.378511623	0.18	0.678071905	0.25	0.35614381	0.18	0.378511623	0.31			1.580145484	1.74			0.263034406	0.23	0.150559677	0.28	0.432959407	0.28	1.201633861	1.22	0.111031312	0.33	0.367371066	0.3
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	10	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	28	hour	1_TK6_Cis_M_4_hr	1_TK6_Cis_0_4_hr	TK6	M	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			0.526068812	0.47	10	1456.95	-0.217591435	0.24	-0.268816758	0.23			-0.152003093	0.13	-0.13606155	0.12	-0.043943348	0.04	-0.168122759	0.12	0.056583528	0.17	0	0			-0.089267338	0.14	-0.074000581	0.13	-0.268816758	0.24	0	0			-0.268816758	0.24	-0.234465254	0.24	0.910732662	1.26			-0.268816758	0.23	0.00279	0.00181	0	0	6.708049252	147.16	-0.089267338	0.13	-0.915935735	0.38	-0.152003093	0.09	-0.13606155	0.08	-0.043943348	0.03	-0.120294234	0.11	0.286881148	0.3	0.214124805	0.27	-0.340075442	0.21	0	0	0.124328135	0.11	0	0.18	-0.104697379	0.06	0.014355293	0.18			0.454175893	0.46	-0.104697379	0.27	-0.120294234	0.09	0.028569152	0.02			-0.184424571	0.02			-0.184424571	0.2	0.097610797	0.06	0.084064265	0.08	0.097610797	0.18	-0.152003093	0.18	0.042644337	0.07
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	10	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	31	hour	1_TK6_Cis_M_7_hr	1_TK6_Cis_0_7_hr	TK6	M	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			10	9522918.87	10	120331.93	0.748461233	0.7	-0.217591435	0.35			0.042644337	0.14	10	3493.02	0.084064265	0.4	0.111031312	0.14	0.286881148	0.22	-0.59946207	0.47			10	1680.39	0.23878686	0.24	0.042644337	0.22	-0.713118852	0.44			10	32642.01	0	0.08	5.352617299	56.53			0.584962501	0.25	-0.59946207	0.47	0	0	5.224580566	51.47	0.070389328	0.18	10	24604.4	-0.13606155	0.03	6.672142433	142.24	10	12709.08	0.584962501	0.52	-1.120294234	0.12	-0.577766999	0.18	-0.01449957	0.13	0	0	9.939696741	1383.54	0.028569152	0.19	0.344828497	0.27	0.250961574	0.15			0.485426827	0.4	0.124328135	0.1	-0.029146346	0.03	0.150559677	0.12			0.545968369	0.68			0.070389328	0.16	-0.152003093	0.19	0.250961574	0.25	0.214124805	0.12	0.097610797	0.17	0.137503524	0.16
Cisplatin	1_TK6_Cisplatin-Taxol	008-00004-0004-000-6	HESI	2004	48	hour	30	ug/ml	Direct DNA damage	1	per study	continuous exposure in medium	Compound was dissolved in DMSO and added to culture medium	DMSO	at or below 1%	48	hour	1_TK6_Cis_H_24_hr	1_TK6_Cis_0_24_hr	TK6	H	ug/ml	4	hour	direct DNA damage	24	hour	Homo	F	T	Lymphoid		Human			-0.089267338	0.37	-0.415037499	0.09	0.298658316	0.16	-0.268816758	0.12			0.275007047	0.17	-0.01449957	0.03	0	0	-0.104697379	0.09	0.35614381	0.15	0	0			0	0.06	-0.120294234	0.13	-0.395928676	0.05	-1.514573173	0.45			0.23878686	0.25	-0.120294234	0.01	0.790772038	0.88			0.895302621	0.37	0	0	0	0	6.726150026	148.31	-0.089267338	0.13	-0.168122759	0.09	-0.810966176	0.16	-0.689659879	0.19	-0.514573173	0.11	-0.234465254	0.08	0.201633861	0.91	-0.120294234	0.19	-0.358453971	0.05	0	0	-0.029146346	0.13	-0.340075442	0.04	-0.13606155	0.03	0.443606651	0.22			0.124328135	0.58	0.704871964	0.46	-0.01449957	0.06	0.084064265	0.11			0.250961574	0.25			0	0.12	-0.473931188	0.18	0.275007047	0.32	1.580145484	2.21	-0.286304185	0.11	0.214124805	0.17
