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Long-Term Study
Organ Weights Individual Animal
Study Information:
| Chemical Name: | Acetaminophen (4-hydroxyacetanilide) |
| CASRN: | ="103-90-2" |
| Study Number: | C55801 |
| Study Length (Year Completed): |
(N/A) |
| Exposure Route: | DOSED FEED |
| TDMS Number: | 0503502 |
| Sex: | Female |
| Strain and Species: | B6C3F1 Mice |
| Organ Weights Individual Animal Data |
| Measurement Time |
Animal Number |
Dose Group (%) |
Control Code |
Final Body Weight (g) |
| Day 8 |
177 |
0.3 |
|
16.4 |
| Day 8 |
178 |
0.3 |
|
15.4 |
| Day 8 |
179 |
0.3 |
|
18.2 |
| Day 9 |
180 |
0.3 |
|
13.8 |
| Day 251 |
192 |
0.6 |
|
27.6 |
| Day 397 |
28 |
0 |
|
33.8 |
| Day 414 |
160 |
0.3 |
|
36.8 |
| Day 436 |
93 |
0.06 |
|
27.2 |
| Day 449 |
69 |
0.06 |
|
21.6 |
| Day 457 |
16 |
0 |
|
38.4 |
| Day 457 |
23 |
0 |
|
47 |
| Day 457 |
40 |
0 |
|
41 |
| Day 457 |
55 |
0 |
|
57.2 |
| Day 457 |
9 |
0 |
|
47.2 |
| Day 457 |
114 |
0.06 |
|
51.8 |
| Day 457 |
118 |
0.06 |
|
41.4 |
| Day 457 |
120 |
0.06 |
|
39.2 |
| Day 457 |
62 |
0.06 |
|
40.4 |
| Day 457 |
77 |
0.06 |
|
47.8 |
| Day 457 |
89 |
0.06 |
|
40.8 |
| Day 457 |
128 |
0.3 |
|
38.2 |
| Day 457 |
140 |
0.3 |
|
38.6 |
| Day 457 |
143 |
0.3 |
|
42.4 |
| Day 457 |
153 |
0.3 |
|
43.6 |
| Day 457 |
166 |
0.3 |
|
32.4 |
| Day 457 |
174 |
0.3 |
|
39.4 |
| Day 457 |
218 |
0.6 |
|
29.6 |
| Day 457 |
237 |
0.6 |
|
43.8 |
| Day 457 |
238 |
0.6 |
|
46.8 |
| Day 458 |
25 |
0 |
|
26 |
| Day 458 |
26 |
0 |
|
55.8 |
| Day 458 |
38 |
0 |
|
39.9 |
| Day 458 |
43 |
0 |
|
42 |
| Day 458 |
45 |
0 |
|
46.6 |
| Day 458 |
113 |
0.06 |
|
39.6 |
| Day 458 |
68 |
0.06 |
|
38.6 |
| Day 458 |
79 |
0.06 |
|
44 |
| Day 458 |
92 |
0.06 |
|
36 |
| Day 458 |
131 |
0.3 |
|
40.6 |
| Day 458 |
138 |
0.3 |
|
42.8 |
| Day 458 |
142 |
0.3 |
|
55.2 |
| Day 458 |
161 |
0.3 |
|
32.6 |
| Day 458 |
182 |
0.6 |
|
41 |
| Day 458 |
184 |
0.6 |
|
36.6 |
| Day 458 |
214 |
0.6 |
|
50.4 |
| Day 458 |
219 |
0.6 |
|
45.2 |
| Day 458 |
231 |
0.6 |
|
51.6 |
| Day 458 |
234 |
0.6 |
|
40.8 |
| Day 458 |
240 |
0.6 |
|
45.6 |
| Day 480 |
164 |
0.3 |
|
35.2 |
| Day 488 |
135 |
0.3 |
|
26.4 |
| Day 491 |
5 |
0 |
|
21.4 |
| Day 506 |
17 |
0 |
|
29.2 |
| Day 516 |
85 |
0.06 |
|
40.8 |
| Day 516 |
145 |
0.3 |
|
38.4 |
| Day 522 |
191 |
0.6 |
|
46.8 |
| Day 534 |
29 |
0 |
|
32.2 |
| Day 534 |
58 |
0 |
|
41.4 |
| Day 534 |
141 |
0.3 |
|
30.8 |
| Day 536 |
3 |
0 |
|
28.2 |
| Day 536 |
222 |
0.6 |
|
35.4 |
| Day 540 |
152 |
0.3 |
|
30.8 |
| Day 547 |
63 |
0.06 |
|
25 |
| Day 549 |
117 |
0.06 |
|
30.8 |
| Day 549 |
144 |
0.3 |
|
31.6 |
| Day 551 |
66 |
0.06 |
|
35 |
| Day 551 |
149 |
0.3 |
|
29 |
| Day 551 |
176 |
0.3 |
|
50.6 |
| Day 555 |
30 |
0 |
|
32.4 |
| Day 564 |
35 |
0 |
|
47.1 |
| Day 579 |
229 |
0.6 |
|
28.4 |
| Day 593 |
233 |
0.6 |
|
45.8 |
| Day 596 |
220 |
0.6 |
|
27.2 |
| Day 599 |
102 |
0.06 |
|
32.2 |
| Day 607 |
151 |
0.3 |
|
37 |
| Day 610 |
121 |
0.3 |
|
33.6 |
| Day 611 |
22 |
0 |
|
29.4 |
| Day 614 |
98 |
0.06 |
|
34.2 |
| Day 620 |
194 |
0.6 |
|
32.2 |
| Day 631 |
196 |
0.6 |
|
30.6 |
| Day 632 |
200 |
0.6 |
|
42 |
| Day 633 |
107 |
0.06 |
|
31.6 |
| Day 634 |
2 |
0 |
|
31.6 |
| Day 634 |
86 |
0.06 |
|
36.6 |
| Day 635 |
42 |
0 |
|
32.6 |
| Day 635 |
203 |
0.6 |
|
24.8 |
| Day 638 |
110 |
0.06 |
|
28.8 |
| Day 638 |
67 |
0.06 |
|
31.4 |
| Day 639 |
136 |
0.3 |
|
25.8 |
| Day 642 |
10 |
0 |
|
36 |
| Day 642 |
7 |
0 |
|
46.4 |
| Day 642 |
127 |
0.3 |
|
36.6 |
| Day 642 |
205 |
0.6 |
|
51.6 |
| Day 647 |
46 |
0 |
|
41 |
| Day 653 |
39 |
0 |
|
31.8 |
| Day 659 |
155 |
0.3 |
|
28.2 |
| Day 659 |
156 |
0.3 |
|
37.4 |
| Day 660 |
8 |
0 |
|
43 |
| Day 661 |
116 |
0.06 |
|
38.6 |
| Day 661 |
91 |
0.06 |
|
44.8 |
| Day 661 |
201 |
0.6 |
|
27 |
| Day 667 |
109 |
0.06 |
|
39.4 |
| Day 678 |
108 |
0.06 |
|
31.6 |
| Day 680 |
101 |
0.06 |
|
37.8 |
| Day 684 |
37 |
0 |
|
32.6 |
| Day 684 |
139 |
0.3 |
|
26.4 |
| Day 684 |
167 |
0.3 |
|
34 |
| Day 691 |
106 |
0.06 |
|
32.8 |
| Day 701 |
49 |
0 |
|
34.6 |
| Day 701 |
168 |
0.3 |
|
27.8 |
| Day 702 |
4 |
0 |
|
34 |
| Day 705 |
150 |
0.3 |
|
36.4 |
| Day 715 |
51 |
0 |
|
43.4 |
| Day 716 |
134 |
0.3 |
|
31 |
| Day 719 |
20 |
0 |
|
33.4 |
| Day 722 |
57 |
0 |
|
37.8 |
| Day 726 |
48 |
0 |
|
44.6 |
| Day 726 |
137 |
0.3 |
|
31 |
| Day 730 |
181 |
0.6 |
|
34.4 |
| Day 730 |
183 |
0.6 |
|
45.2 |
| Day 730 |
185 |
0.6 |
|
39.8 |
| Day 730 |
186 |
0.6 |
|
48 |
| Day 730 |
187 |
0.6 |
|
40.8 |
| Day 730 |
188 |
0.6 |
|
53 |
| Day 730 |
189 |
0.6 |
|
51.8 |
| Day 730 |
190 |
0.6 |
|
46.2 |
| Day 730 |
193 |
0.6 |
|
47.4 |
| Day 730 |
195 |
0.6 |
|
44 |
| Day 730 |
197 |
0.6 |
|
40.4 |
| Day 730 |
199 |
0.6 |
|
36.8 |
| Day 730 |
202 |
0.6 |
|
46.4 |
| Day 730 |
204 |
0.6 |
|
46 |
| Day 730 |
206 |
0.6 |
|
53.8 |
| Day 730 |
207 |
0.6 |
|
52.2 |
| Day 730 |
208 |
0.6 |
|
43 |
| Day 730 |
209 |
0.6 |
|
31.2 |
| Day 730 |
210 |
0.6 |
|
52.8 |
| Day 730 |
211 |
0.6 |
|
53.2 |
| Day 730 |
212 |
0.6 |
|
46.6 |
| Day 730 |
213 |
0.6 |
|
43.4 |
| Day 730 |
215 |
0.6 |
|
45.2 |
| Day 730 |
216 |
0.6 |
|
42.4 |
| Day 730 |
217 |
0.6 |
|
41 |
| Day 730 |
221 |
0.6 |
|
43.2 |
| Day 730 |
223 |
0.6 |
|
40 |
| Day 730 |
224 |
0.6 |
|
40.8 |
| Day 730 |
225 |
0.6 |
|
42.6 |
| Day 730 |
227 |
0.6 |
|
45.4 |
| Day 730 |
230 |
0.6 |
|
46 |
| Day 731 |
61 |
0.06 |
|
39.2 |
| Day 731 |
64 |
0.06 |
|
48.6 |
| Day 731 |
65 |
0.06 |
|
36.2 |
| Day 731 |
70 |
0.06 |
|
40.2 |
| Day 731 |
122 |
0.3 |
|
47.4 |
| Day 731 |
123 |
0.3 |
|
40 |
| Day 731 |
124 |
0.3 |
|
45.2 |
| Day 731 |
125 |
0.3 |
|
39.2 |
| Day 731 |
126 |
0.3 |
|
39.6 |
| Day 731 |
130 |
0.3 |
|
34.8 |
| Day 731 |
132 |
0.3 |
|
36.6 |
| Day 731 |
133 |
0.3 |
|
48 |
| Day 731 |
146 |
0.3 |
|
25.2 |
| Day 731 |
147 |
0.3 |
|
36.8 |
| Day 731 |
148 |
0.3 |
|
50.4 |
| Day 731 |
154 |
0.3 |
|
32 |
| Day 731 |
157 |
0.3 |
|
37.4 |
| Day 731 |
158 |
0.3 |
|
43 |
| Day 731 |
159 |
0.3 |
|
39.2 |
| Day 731 |
162 |
0.3 |
|
39.8 |
| Day 731 |
163 |
0.3 |
|
42.6 |
| Day 731 |
165 |
0.3 |
|
48 |
| Day 731 |
169 |
0.3 |
|
46.2 |
| Day 731 |
170 |
0.3 |
|
40.6 |
| Day 731 |
171 |
0.3 |
|
51.8 |
| Day 731 |
172 |
0.3 |
|
36.2 |
| Day 731 |
173 |
0.3 |
|
33.4 |
| Day 731 |
175 |
0.3 |
|
47.2 |
| Day 731 |
198 |
0.6 |
|
52 |
| Day 731 |
226 |
0.6 |
|
37.8 |
| Day 731 |
228 |
0.6 |
|
41.6 |
| Day 731 |
235 |
0.6 |
|
44 |
| Day 731 |
236 |
0.6 |
|
42.4 |
| Day 731 |
239 |
0.6 |
|
42.6 |
| Day 732 |
1 |
0 |
|
40.2 |
| Day 732 |
11 |
0 |
|
54.2 |
| Day 732 |
13 |
0 |
|
49.8 |
| Day 732 |
14 |
0 |
|
41 |
| Day 732 |
15 |
0 |
|
65.4 |
| Day 732 |
18 |
0 |
|
54 |
| Day 732 |
19 |
0 |
|
38.4 |
| Day 732 |
100 |
0.06 |
|
36 |
| Day 732 |
103 |
0.06 |
|
64.6 |
| Day 732 |
104 |
0.06 |
|
42.4 |
| Day 732 |
105 |
0.06 |
|
49.2 |
| Day 732 |
111 |
0.06 |
|
37.8 |
| Day 732 |
112 |
0.06 |
|
38.2 |
| Day 732 |
115 |
0.06 |
|
45.2 |
| Day 732 |
119 |
0.06 |
|
37.8 |
| Day 732 |
71 |
0.06 |
|
39.2 |
| Day 732 |
72 |
0.06 |
|
41.2 |
| Day 732 |
73 |
0.06 |
|
41.4 |
| Day 732 |
74 |
0.06 |
|
39.4 |
| Day 732 |
75 |
0.06 |
|
35.2 |
| Day 732 |
76 |
0.06 |
|
36.4 |
| Day 732 |
78 |
0.06 |
|
50 |
| Day 732 |
80 |
0.06 |
|
43 |
| Day 732 |
81 |
0.06 |
|
42.8 |
| Day 732 |
82 |
0.06 |
|
50.2 |
| Day 732 |
83 |
0.06 |
|
45.4 |
| Day 732 |
84 |
0.06 |
|
41.4 |
| Day 732 |
87 |
0.06 |
|
56.8 |
| Day 732 |
88 |
0.06 |
|
50.8 |
| Day 732 |
90 |
0.06 |
|
44.2 |
| Day 732 |
94 |
0.06 |
|
44.2 |
| Day 732 |
95 |
0.06 |
|
45 |
| Day 732 |
96 |
0.06 |
|
38 |
| Day 732 |
97 |
0.06 |
|
41.4 |
| Day 732 |
99 |
0.06 |
|
47.2 |
| Day 732 |
129 |
0.3 |
|
34.2 |
| Day 732 |
232 |
0.6 |
|
33.8 |
| Day 733 |
12 |
0 |
|
56.8 |
| Day 733 |
21 |
0 |
|
47.2 |
| Day 733 |
24 |
0 |
|
56.4 |
| Day 733 |
27 |
0 |
|
34.4 |
| Day 733 |
31 |
0 |
|
46.4 |
| Day 733 |
32 |
0 |
|
36.2 |
| Day 733 |
33 |
0 |
|
45.2 |
| Day 733 |
34 |
0 |
|
43.8 |
| Day 733 |
36 |
0 |
|
47.6 |
| Day 733 |
41 |
0 |
|
32.2 |
| Day 733 |
44 |
0 |
|
36 |
| Day 733 |
47 |
0 |
|
42.2 |
| Day 733 |
50 |
0 |
|
40.6 |
| Day 733 |
52 |
0 |
|
50 |
| Day 733 |
53 |
0 |
|
55 |
| Day 733 |
54 |
0 |
|
39.6 |
| Day 733 |
56 |
0 |
|
26.6 |
| Day 733 |
59 |
0 |
|
48.2 |
| Day 733 |
6 |
0 |
|
53 |
| Day 733 |
60 |
0 |
|
48.6 |
| Abbreviations: |
|
NA: Not Available
|