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Study Information
Study Attribute Value
CEBS Accession Number: 002-01728-0016-0000-7
Chemical Name: Bisphenol A
CASRN: 80-05-7
NTP Study Type: Genetic Toxicology - Rodent Cytogenetics
NTP Study ID: 070061_CA
Study Result: Positive (Nonstandard Protocol)

Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/22/86 17 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 17 hour 0.8273
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
100         
 8 9.00 ± 1.73 0.0001
Test Chemical Bisphenol A 
62.5       
 8 2.50 ± 0.50 0.5875
  
125         
 8 2.50 ± 0.73 0.5875
  
250         
 8 1.75 ± 0.70 0.8299
Vehicle Control No Stressor 
 0         
 8 2.75 ± 1.13 0.0000


Test Type Start Date Sample Time (h) Species Sex Tissue Protocol Trend Test P
CA 09/17/90 36 Mouse Male Bone Marrow Intraperitoneal Injection x 1/study, 36 hour 0.0137
Test Group Dose
(mg/kg)		 n Percent Cells w/ Aberrations
(Mean ± SEM)		 Pairwise P
Positive Control Dimethylbenzanthracene 
50         
 8 28.25 ± 3.75 0.0000
Test Chemical Bisphenol A 
37.5       
 8 1.00 ± 0.38 0.5000
  
75         
 8 1.75 ± 0.88 0.1812
  
150         
 8 2.75 ± 1.06 0.0340
Vehicle Control No Stressor 
 0         
 8 1.00 ± 0.53 0.0000


Footnotes:
IP/IJ: Intraperitoneal Injection
INHAL: Inhalation
n: Number of animals analyzed