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Benzo(a)pyrene (50-32-8)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020139

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Benzo(a)pyrene (50-32-8).
Rodent Cytogenetics
CA
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Benzo(a)pyrene (50-32-8).
Mammalian Cell Mutagenicity
View
  • Positive
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Benzo(a)pyrene (50-32-8).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Benzo(a)pyrene (50-32-8).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Benzo(a)pyrene (50-32-8).
Bacterial Mutagenicity
View
  • Positive
View
  • Positive

Citation Information

NTP. Benzo(a)pyrene (50-32-8). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
Valencia, R., Mason, J.M., and Zimmering, S. Chemical mutagenesis testing in Drosophila. IV. Interlaboratory comparison of mutagenicity tests after treatment of larvae. Environ. Molec. Mutagen. Vol. 14 (1989) 238-244
The Power of Resolution: Contextualized Understanding of Biological Responses to Liver Injury Chemicals using High Throughput Transcriptomics and Benchmark Concentration Modeling Ramaiahgari SC, Auerbach SS, Saddler TO, Rice JR, Dunlap PE, Sipes NS, DeVito MJ, Shah RR, Bushel PR, Merrick BA, Paules RS, Ferguson SS

Toxicological Sciences (2019) DOI: https://doi.org/10.1093/toxsci/kfz065 PMID: 30850835
CEBS DOI: https://doi.org/10.22427/NTP-DATA-002-00058-0001-0000-6
SRA No. SRP166108; BioProject No. PRJNA497448

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Benzo(a)pyrene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 193997
Summary Data
Genetic Toxicity Evaluation of Benzo(a)pyrene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 793997
Summary Data

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Screen for Developmental Toxicity in Zebrafish- Study 1
Results

NTP Data Collections