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Hallmark Gene Sets Annotations

DOI: https://doi.org/10.22427/NTP-DATA-022-00002-0004-000-0

Annotation of Hallmark Gene Sets using NextBio platform to identify correlations between Hallmark Gene Sets and gene expression studies focusing on liver, heart and kidney tissue in rodents and humans. Additionally, correlations to gene expression studies in other tissues in rodents are described herein.

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Hallmark Gene Set Name Tissue Expression Associated Hallmark Sets Up-regulation Down-regulation MsigDB Interpretation Canonical Pathway Associations Mechanistic Interpretation Highest 3 Correlate Drugmatrix Studies In Liver Highest 3 Correlate Drugmatrix Studies In Heart Highest 3 Correlate Drugmatrix Studies In Kidney Gene Set Enrichment Analysis Gene List CASRN