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Bioassay Genetox Conclusion Dataset

DOI: https://doi.org/10.22427/NTP-DATA-022-00002-0002-000-8

The dataset provides DTT conclusions from bioassay level of evidence, and genetic toxicology measures of bacterial mutagenicity, micronucleus, and comet assay; February 2022 version.

In TR544 and subsequent reports, for studies showing multiple chemical-related neoplastic effects that if considered individually would be assigned to different levels of evidence categories. In a study with clear evidence of carcinogenic activity at some tissue sites, other responses that alone might be deemed some evidence are indicated as “were also related” to chemical exposure. In studies with clear or some evidence of carcinogenic activity, other responses that alone might be termed equivocal evidence are indicated as “may have been” related to chemical exposure.  These levels of evidence are now included in this dataset.

 

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Chemical Name Male Rat Chronic Bioassay Level of Evidence Female Rat Chronic Bioassay Level of Evidence Male Mouse Chronic Bioassay Level of Evidence Female Mouse Chronic Bioassay Level of Evidence Male Hamster Chronic Bioassay Level of Evidence Female Hamster Chronic Bioassay Level of Evidence Male Fish Chronic Bioassay Level of Evidence Female Fish Chronic Bioassay Level of Evidence Multiple Level of Evidence Conclusion? T/F Bacterial Mutagenicity Conclusion Male Rat Micronucleus Conclusion Female Rat Micronucleus Conclusion Male Mouse Micronucleus Conclusion Female Mouse Micronucleus Conclusion In Vitro Micronucleus Conclusion Male Rat Comet Assay Conclusion Female Rat Comet Assay Conclusion Male Mouse Comet Assay Conclusion Female Mouse Comet Assay Conclusion NTP Publication Number DTXSID CASRN