TR-602: Tris(Chloropropyl)phosphate (13674-84-5)
Publications
TR-602
Toxicity Studies of tris(2-Chloroisopropyl)phosphate Administered via Dosed Feed to Harlan Sprague-Dawley Rats and B6C3F1/N Mice
Study Data
Toxicity and Carcinogenicity Studies
3-Month (with Perinatal Exposure) Evaluation of the Toxicity (C20712-01) of tris(2-Chloroisopropyl)phosphate (13674-84-5) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Study Tables
- Adjusted Pup Body Weights (194 kB)
- E03 - Growth Curves (58 kB)
- E04 - Mean Body Weights and Survival Table (12 kB)
- E05 - Clinical Observations Summary (18 kB)
- E06 - Mean Feed Consumption by Treatment Group (15 kB)
- E08 - Feed and Compound Consumption Table (22 kB)
- Gestational Body Weights (224 kB)
- Gestational and Lactational Chemical Consumption (193 kB)
- Gestational and Lactational Food Consumption (197 kB)
- Image Analysis of Thymus Size for Male and Female Rats (114 kB)
- Lactational Body Weights (192 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (33 kB)
- P04 - Neoplasms by Individual Animal (203 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (208 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (117 kB)
- P14 - Individual Animal Pathology Data (238 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (34 kB)
- PA06 - Organ Weights Summary (74 kB)
- PA41 - Clinical Chemistry Summary (156 kB)
- PA43 - Hematology Summary (210 kB)
- PND 1 Litter and Pup Body Weight Data (197 kB)
- PND 4-21 Live Litter Size and Survival (202 kB)
- R02 - Reproductive Performance Summary (40 kB)
- R06 - Andrology Summary (49 kB)
Individual Animal Data
- Female Individual Animal Clinical Observations (3 kB)
- Female Individual Animal Non Neoplastic Pathology Data (20 kB)
- Female Individual Animal Survival (10 kB)
- Female Individual Animal Terminal Body Weight Data (16 kB)
- Female Individual Body Weight Data (39 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Body Weight Data F1 Post Wean (66 kB)
- Individual Animal Clinical Chemistry Data (12 kB)
- Individual Animal Clinical Observation Data F1 Post Wean (59 kB)
- Individual Animal DamID and PupID Data (8 kB)
- Individual Animal Food Consumption Data F1 Post Wean (118 kB)
- Individual Animal Gross Pathology Data F1 (96 kB)
- Individual Animal Hematology Data (15 kB)
- Individual Animal Histo Pathology Data F1 (21 kB)
- Individual Animal Organ Weight Data (11 kB)
- Individual Animal Removal Reasons Data (10 kB)
- Individual Animal Reproductive Performance Data (8 kB)
- Male Individual Animal Body Weight (29 kB)
- Male Individual Animal Clinical Observations (6 kB)
- Male Individual Animal Non Neoplastic Pathology Data (32 kB)
- Male Individual Animal Survival (10 kB)
- Male Individual Animal Terminal Body Weight Data (16 kB)
3-Month Evaluation of the Toxicity (C20712-02) of tris(Chloropropyl)phosphate (13674-84-5) in B6C3F1/N Mice Exposed via Dosed Feed
Study Tables
- E03 - Growth Curves (442 kB)
- E04 - Mean Body Weights and Survival Table (18 kB)
- E05 - Clinical Observations Summary (11 kB)
- E06 - Mean Feed Consumption by Treatment Group (16 kB)
- E08 - Feed and Compound Consumption Table (24 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (29 kB)
- P04 - Neoplasms by Individual Animal (204 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (34 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (203 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (53 kB)
- P14 - Individual Animal Pathology Data (263 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (30 kB)
- PA06 - Organ Weights Summary (88 kB)
- PA43 - Hematology Summary (270 kB)
- R06 - Andrology Summary (48 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (36 kB)
- Female Individual Animal Non Neoplastic Pathology Data (12 kB)
- Female Individual Animal Survival Data (11 kB)
- Female Individual Animal Terminal Body Weight Data (27 kB)
- Individual Animal Andrology Data (8 kB)
- Individual Animal Hematology Data (17 kB)
- Individual Animal Organ Weight Data (11 kB)
- Male Individual Animal Body Weight Data (36 kB)
- Male Individual Animal Non Neoplastic Pathology Data (23 kB)
- Male Individual Animal Survival Data (11 kB)
- Male Individual Animal Terminal Body Weight Data (27 kB)
Evaluation of the Chronic (with Perinatal Exposure) Toxicity and Carcinogenicity (C20712-03) of Tris(Chloropropyl) phosphate (1367-84-5) in Harlan Sprague Dawley Rats Exposed via Dosed Feed
Study Tables
- Adjusted Pup Body Weights (50 kB)
- E01 - Animal Removal Summary By Treatment Group - Dam Gestation (7 kB)
- E01 - Animal Removal Summary By Treatment Group - Dam Lactation (7 kB)
- E01 - Animal Removal Summary By Treatment Group - Female Pup (7 kB)
- E01 - Animal Removal Summary By Treatment Group - Male Pup (7 kB)
- E01 - Animal Removal Summary by Treatment Group (13 kB)
- E02 - Animals Removed from Experiment (174 kB)
- E02 - Animals Removed from Experiment - Dam Gestation (51 kB)
- E02 - Animals Removed from Experiment - Dam Lactation (33 kB)
- E02 - Animals Removed from Experiment - Female Pup (162 kB)
- E02 - Animals Removed from Experiment - Male Pup (172 kB)
- E03 - Growth Curves (73 kB)
- E03 - Growth Curves - Dam Gestation (29 kB)
- E03 - Growth Curves - Dam Lactation (30 kB)
- E03 - Growth Curves - Female Pup (29 kB)
- E03 - Growth Curves - Male Pup (29 kB)
- E04 - Mean Body Weights and Survival Table (20 kB)
- E05 - Clinical Observations Summary (27 kB)
- E06 - Mean Feed Consumption by Treatment Group (28 kB)
- E08 - Feed and Compound Consumption Table (42 kB)
- E12 - Animal History (2 mB)
- E12 - Animal History - Dam Gestation (315 kB)
- E12 - Animal History - Dam Lactation (292 kB)
- E12 - Animal History - Female Pup (2 mB)
- E12 - Animal History - Male Pup (2 mB)
- Gestational Body Weights (224 kB)
- Gestational and Lactational Chemical Consumption (152 kB)
- Gestational and Lactational Food Consumption (156 kB)
- I05 - Clinical Observation Summary.pdf (70 kB)
- Lactational Body Weights (198 kB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (65 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (67 kB)
- P04 - Neoplasms by Individual Animal (901 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (56 kB)
- P08 - Statistical Analysis of Primary Tumors (211 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (1 mB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (607 kB)
- P11 - Statistical Analysis of Survival Data (22 kB)
- P14 - Individual Animal Pathology Data (2 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (774 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (71 kB)
- P40 - Survival Curves (495 kB)
- PA48 - Summary of Tissue Concentration (79 kB)
- PND 1 Litter Size and Pup Body Weight Data (19 kB)
- PND 4-28 Live Litter Size and Survival (199 kB)
- R02 - Reproductive Performance Summary (39 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data (502 kB)
- Female Individual Animal Body Weight Data All Animals - Dam Gestation (55 kB)
- Female Individual Animal Body Weight Data All Animals - Dam Lactation (54 kB)
- Female Individual Animal Body Weight Data All Animals - Female Pup (286 kB)
- Female Individual Animal Neoplastic Pathology Data (184 kB)
- Female Individual Animal Non Neoplastic Pathology Data (931 kB)
- Female Individual Animal Survival (42 kB)
- Female Individual Animal Survival Data - Female Pup (155 kB)
- Female Individual Animal Survival Data - Female Pup - Dam Gestation (32 kB)
- Female Individual Animal Survival Data - Female Pup - Dam Lactation (27 kB)
- Female Individual Animal Terminal Body Weight Data (71 kB)
- Female Individual Animal Terminal Body Weight Data - Dam Lactation (48 kB)
- Female Individual Animal Terminal Body Weight Data - Female Pup (274 kB)
- Female Individual Animal Terminal Body Weight Data - Female Pup - Dam Gestation (54 kB)
- Female Individual Body Weight All Animals (502 kB)
- Female Individual Clinical Observations (254 kB)
- Individual Animal Clinical Observations Data (10 kB)
- Individual Animal DamID and PupID Data (24 kB)
- Individual Animal Reproductive Performance Data (12 kB)
- Individual Animal Tissue Concentration Data (45 kB)
- Individual Pup Census and Litter Weight by Sex Data (29 kB)
- Male Individual Animal Body Weight Data All Animals - Male Pup (309 kB)
- Male Individual Animal Neoplastic Pathology Data (151 kB)
- Male Individual Animal Non Neoplastic Pathology Data (931 kB)
- Male Individual Animal Survival (42 kB)
- Male Individual Animal Survival Data - Male Pup (167 kB)
- Male Individual Animal Terminal Body Weight Data (71 kB)
- Male Individual Animal Terminal_Body Weight Data - Male Pup (297 kB)
- Male Individual Body Weight (473 kB)
- Male Individual Body Weight All Animals (473 kB)
- Male Individual Clinical Observations (170 kB)
Evaluation of the Chronic Toxicity and Carcinogenicity (C20712-04) of Tris(Chloropropyl) phosphate (1367-84-5) in B6C3F1 Mice Exposed via Dosed Feed
Study Tables
- E01 - Animal Removal Summary by Treatment Group (9 kB)
- E02 - Animals Removed from Experiment (87 kB)
- E03 - Growth Curves (472 kB)
- E04 - Mean Body Weights and Survival Table (19 kB)
- E05 - Clinical Observations Summary (12 kB)
- E06 - Mean Feed Consumption by Treatment Group (26 kB)
- E08 - Feed Water and Compound Consumption Table (37 kB)
- E12 - Animal History (1 mB)
- P02 - Incidence Rates of Neoplasms by Anatomic Site (51 kB)
- P03 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site (40 kB)
- P04 - Neoplasms by Individual Animal (665 kB)
- P05 - Incidence Rates of Neoplasms by Anatomic Site (Systemic Lesions Abridged) (45 kB)
- P08 - Statistical Analysis of Primary Tumors (159 kB)
- P09 - Non-Neoplastic Lesions by Individual Animal (594 kB)
- P10 - Statistical Analysis of Non-Neoplastic Lesions (165 kB)
- P11 - Statistical Analysis of Survival Data (17 kB)
- P14 - Individual Animal Pathology Data (1 mB)
- P17 - Neoplasms By Individual Animal (Systemic Lesions Abridged) (559 kB)
- P18 - Incidence Rates of Non-Neoplastic Lesions by Anatomic Site with Average Severity Grades (42 kB)
- P40 - Survival Curves (449 kB)
- PA48 - Summary of Tissue Concentration (48 kB)
Individual Animal Data
- Female Individual Animal Body Weight Data All Animals (301 kB)
- Female Individual Animal Clinical Observations (20 kB)
- Female Individual Animal Neoplastic Pathology Data (108 kB)
- Female Individual Animal Non Neoplastic Pathology Data (352 kB)
- Female Individual Animal Survival Data (34 kB)
- Female Individual Animal Terminal Body Weight Data (57 kB)
- Male Individual Animal Body Weight Data All Animals (334 kB)
- Male Individual Animal Clinical Observations (31 kB)
- Male Individual Animal Neoplastic Pathology Data (122 kB)
- Male Individual Animal Non Neoplastic Pathology Data (212 kB)
- Male Individual Animal Survival Data (34 kB)
- Male Individual Animal Terminal Body Weight Data (57 kB)