phenol,4,4-(2,2,2-triflouro-1-(trifluromethyl)ethylidene) (1478-61-1)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7037717
Publications
DART-08
Prenatal Development Studies of Bisphenol AF in Sprague Dawley (Sprague Dawley SD) Rats (Dosed Feed Studies) CASRN: 1478-61-1
Waidyanatha S, SR Black, CR Croutch, BJ Collins, MAR Silinski, S Kerns, V Sutherland, V Godfrey Robinson, K Aillon, RA Fernando, E Mutlu and TR Fennell. Comparative toxicokinetics of bisphenol S and bisphenol AF in male rats and mice following repeated exposure via feed [Journal Article] Xenobiotica (2020) [In Press]
Binding of Bisphenol A, Bisphenol AF, and Bisphenol S on the Androgen Receptor: Coregulator Recruitment and Stimulation of Potential Interaction Sites
Lalith Perera, Yin Li, Laurel A. Coons, Rene Houtman, Rinie van Beuningen, Bonnie Goodwin, Scott S. Auerbach, and Christina T. Teng.
Toxicology in Vitro (2017) DOI: https://doi.org/10.1016/j.tiv.2017.07.020 PMID: 28751236
Toxicology in Vitro (2017) DOI: https://doi.org/10.1016/j.tiv.2017.07.020 PMID: 28751236
Evaluation of Prenatal Exposure to Bisphenol Analogues on Development and Long-Term Health of the Mammary Gland in Female Mice
Tucker DK, Hayes Bouknight S, Brar SS, Kissling G, Fenton S
Environmental Health Perspectives(2018) DOI: https://doi.org/10.1289/EHP3189 PMID:30102602
DOI: https://doi.org/10.22427/NTP-DATA-021-00004-0001-0000-8
Environmental Health Perspectives(2018) DOI: https://doi.org/10.1289/EHP3189 PMID:30102602
DOI: https://doi.org/10.22427/NTP-DATA-021-00004-0001-0000-8
An investigation of systemic exposure to bisphenol AF during critical periods of development in the rat
Suramya Waidyanatha, Bradley J. Collins, Helen Cunny, Kristin Aillon, Felicia Riordan, Katie Turner, and Vicki Sutherland
DOI: https://doi.org/10.22427/NTP-DATA-002-03263-0010-0000-7
DOI: https://doi.org/10.22427/NTP-DATA-002-03263-0010-0000-7
Toxicokinetic Evaluation (K08002D) of Bisphenol AF (1478-61-1) in Harlan Sprague Dawley Rats and B6C3F1/N Mice Exposed via Dosed Feed
DOI:
https://doi.org/10.22427/NTP-DATA-002-03263-0011-0000-8
Study Data
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Bisphenol AF (1478-61-1) in Micronucleus Study G08002B in Harlan Sprague-Dawley Rats
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Bisphenol AF in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G08002
Summary Data
- G06 - Ames Summary Data (79 KB)
Other NTP Studies
Modified One Generation (MOG) Dose Range Finding Toxicity Study (MOG08002) of Bisphenol AF (1478-61-1) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Study Tables
- I01 - Animal Removal Summary (48 kB)
- I02 - Animal Removals (320 kB)
- I03 - Growth Curve (652 kB)
- I03C - Growth Curve (673 kB)
- I04 - Mean Body Weights and Survival (211 kB)
- I04G - Mean Body Weight Gain (119 kB)
- I05 - Clinical Observations Summary (90 kB)
- I05P - Pup Clinical Observations Summary (179 kB)
- I06 - Mean Feed Consumption (119 kB)
- I08 - Mean Test Compound Consumption (96 kB)
- PA46 - Summary of Gross Pathology (106 kB)
- R01 - Multigeneration Cross Reference (938 kB)
- R02 - Reproductive Performance Summary (43 kB)
- R03 - Summary of Litter Data (94 kB)
- R19 - Pup Mean Body Weight Summary (203 kB)
- R19C - Pup Growth Curve (905 kB)
- R19G - Pup Mean Body Weight Gain (155 kB)
- R20 - Pup Necropsy Summary (126 kB)
Individual Animal Data
- Individual Animal Body Weight Data (41 kB)
- Individual Animal Clinical Observations Data (78 kB)
- Individual Animal Consumption Data (38 kB)
- Individual Animal Gross Pathology Data (5 kB)
- Individual Animal Litter Data (49 kB)
- Individual Animal Pup Body Weight Data (82 kB)
- Individual Animal Pup Clinical Observations Data (341 kB)
- Individual Animal Pup Necropsy Data (8 kB)
- Individual Animal Removal Reasons Data (6 kB)
- Individual Animal Reproductive Performance Data (8 kB)
Modified One Generation (MOG) Toxicity Study (MOG08002B) of Bisphenol AF (1478-61-1) in Harlan Sprague-Dawley Rats Exposed via Dosed Feed
Study Tables
- F1 All Cohorts Vaginal Cytology Plots (83 kB)
- F1 All Cohorts Vaginal Cytology Summary 2020-08-20 (26 kB)
- F2 Vaginal Cytology Summary 2020-08-20 (35 kB)
- I01 - Animal Removal Summary (174 kB)
- I02 - Animal Removals (4 mB)
- I03 - Growth Curve (3 mB)
- I03C - Growth Curve (2 mB)
- I04 - Mean Body Weight Summary (543 kB)
- I04G - Mean Body Weight Gain (375 kB)
- I05 - Clinical Observations Summary (498 kB)
- I05P - Pup Clinical Observations Summary (366 kB)
- I06 - Mean Feed Consumption (499 kB)
- I08 - Mean Test Compound Consumption (366 kB)
- PA02R - Neoplastic Lesion Summary with Percent and Litter Incidence (1 mB)
- PA03R - Non-Neoplastic Lesion Summary with Percent and Litter Incidence (1 mB)
- PA05R - Incidence Rates of Neoplastic Lesions with Litter Incidence Systemic Lesions Abridged (1 mB)
- PA06R - Organ Weights Summary (286 kB)
- PA08R - Statistical Analysis of Neoplastic Lesions with Litter Incidence (928 kB)
- PA10R - Statistical Analysis of Non-Neoplastic Lesions with Litter Incidence (1 mB)
- PA14 - Individual Animal Pathology Data (5 mB)
- PA18R - Non-Neoplastic Lesion Summary with Mean Severity Grade and Litter Incidence (1 mB)
- PA41 - Clinical Chemistry Summary (148 kB)
- PA43 - Hematology Summary (178 kB)
- PA46R - Summary of Gross Pathology with Litter Incidence (2 mB)
- PA48 - Summary of Tissue Concentration (70 kB)
- R01 - Multigeneration Cross Reference (4 mB)
- R02 - Reproductive Performance Summary (73 kB)
- R03 - Summary of Litter Data (141 kB)
- R04 - Anogenital Distance Summary (60 kB)
- R06 - Andrology Summary (77 kB)
- R09 - Uterine Content Summary (78 kB)
- R10 - Fetal Defects (135 kB)
- R11 - Fetal Defect Summary (78 kB)
- R13 - Fetal Defect Cross Reference Summary (109 kB)
- R14 - Developmental Markers Summary (75 kB)
- R14C - Time to Attainment Curves for Testicular Descent (440 kB)
- R16 - Pubertal Markers Summary (104 kB)
- R16C - Time to Attainment Curves for Pubertal Markers (4 mB)
- R19 - Pup Mean Body Weight Summary (374 kB)
- R19C - Pup Growth Curve (2 mB)
- R19G - Mean Body Weight Gain (272 kB)
- R20 - Pup Necropsy Summary (236 kB)
- Vaginal Cytology Markov Model (243 kB)
Individual Animal Data
- F1 Fertility Cohort Vaginal Cytology Plots (98 kB)
- F1 Prechronic Cohort Vaginal Cytology Plots (61 kB)
- F1 Prenatal Cohort Vaginal Cytology Plots (71 kB)
- Individual Animal Andrology Data (23 kB)
- Individual Animal Body Weight Data (587 kB)
- Individual Animal Clinical Chemistry Data (116 kB)
- Individual Animal Clinical Observations Data (3 mB)
- Individual Animal Consumption Data (694 kB)
- Individual Animal Developmental Markers Data (167 kB)
- Individual Animal Gross Pathology Data (414 kB)
- Individual Animal Hematolgy Data (171 kB)
- Individual Animal Histopathology Data (172 kB)
- Individual Animal Litter Data (224 kB)
- Individual Animal Organ Weight Data (95 kB)
- Individual Animal Pup Body Weight Data (463 kB)
- Individual Animal Pup Clinical Observations Data (2 mB)
- Individual Animal Pup Necropsy Data (16 kB)
- Individual Animal Removal Reasons Data (48 kB)
- Individual Animal Reproductive Performance Data (19 kB)
- Individual Animal Teratology Dam Data (10 kB)
- Individual Animal Teratology Fetal Weight Data (28 kB)
- Individual Animal Teratology Implant Findings Data (132 kB)
- Individual Animal Tissue Concentration Data (31 kB)
Toxicokinetic Evaluation (K08002C) of Bisphenol AF (DTXSID7037717) in Rat and Mouse
Data
- Annotated Group Parameters (31 kB)
- Annotated Individual Animal Data (260 kB)
- Original Data - Mice (32 kB)
- Original Data - Rats (48 kB)
- Summary Data - Mice (190 kB)
- Summary Data - Rats (286 kB)